GLA (Gamma-linolenic acid)
Also known as GLA, Gamma-linolenic acid, 18:3 n-6
Gamma-linolenic acid (GLA) is an omega-6 fat the body normally makes from linoleic acid. Unlike most omega-6 fats, it can have anti-inflammatory effects, and it is found in evening primrose, borage, and blackcurrant seed oils.
Why it matters
What it does in your body
- Converted by the body into anti-inflammatory signaling molecules
- Supports skin barrier and moisture
- Building block leading to DGLA
- Part of omega-6 metabolism
Intake guidance
How much you need
There is no intake target for GLA, because the body makes it from the essential fat linoleic acid, which the diet supplies in abundance. It appears in the diet mainly through specialty seed oils and supplements rather than everyday foods.
What affects it
What affects your intake
Body's own production
Healthy adults make GLA from linoleic acid, so it is not a required dietary fat.
Specialty oil sources
Evening primrose, borage, and blackcurrant seed oils are the main dietary and supplement sources.
Conversion to DGLA
GLA is quickly converted to DGLA, which yields anti-inflammatory compounds.
In practice
Good to know
Good to know: GLA is unusual among omega-6 fats because it can dampen inflammation rather than promote it, which is why evening primrose and borage oil are marketed for eczema, joint symptoms, and PMS. Evidence is mixed and generally modest. The body makes its own GLA, so there is no dietary requirement.
Where to get it
Best food sources
The bottom line
GLA is a self-made omega-6 fat with anti-inflammatory potential, sold as evening primrose or borage oil. Evidence for supplements is modest, and there is no dietary need for it.
Track gla (gamma-linolenic acid) automatically
GLA (Gamma-linolenic acid) is one of the 92 nutrients Vora reads from a photo of your meal, so you can see where you stand without weighing or logging by hand.
Sources and method
The classification, roles, and guidance on this page come from the references below, drawing on the Institute of Medicine (now the National Academies) Dietary Reference Intakes and reputable nutrition science.
- National Center for Complementary and Integrative Health
- National Library of Medicine, MedlinePlus
This page is for general education, not medical advice. Reference intakes are population averages for healthy people and do not replace guidance from your doctor or a registered dietitian, especially if you are pregnant, managing a health condition, or considering supplements.